Investigation on the interaction of dietary phenolic acids and their derivatives with biologically significant molecules A multi spectroscopic analysis.

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dc.contributor.advisorBose, Adity
dc.creator.researcherMondal, Prasenjit
dc.date.accessioned2024-07-26T10:15:29Z
dc.date.available2024-07-26T10:15:29Z
dc.description.abstractThe Phenolic compounds (PCs) are the well-known plant secondary metabolites gaining popularity due to their diverse biological properties. The goal of the current work is to explore the interaction of two phenolic acids and their derivatives with biological macromolecule (DNA of calf thymus). The diverse biological properties of PCs were also explored in various solvent systems to understand its bioavailability and biological activity in different solvent system. We have also studied the effect of UVB exposure with and without phenolic acids (PAs) in-vitro. The sensing activity of PAs based Ni nanoparticle was also observed and it was found that the nanoparticle successfully sense the permanganate ions in the micromolar range. Finally, the interaction pattern of PAs with beta-casein was observed using various experimental and theoretical tools. The results demonstrated improved bio-efficacy of the PAs in terms of antioxidant activity and aqueous solubility. In conclusion, the clinical efficacy of natural PAs may play an important role in protection against adverse effects related to oxidative damage.en_US
dc.description.searchVisibilitytrueen_US
dc.format.mimetypeapplication/pdfen_US
dc.identifier.urihttps://www.presiuniv.ac.inen_US
dc.identifier.urihttp://www.presiuniv.ndl.iitkgp.ac.in/handle/123456789/2426
dc.language.isoengen_US
dc.rights.accessRightsauthorizeden_US
dc.sourcePresidency Universityen_US
dc.source.urihttps://www.presiuniv.ac.inen_US
dc.subjectSinapic aciden_US
dc.subjectGallic aciden_US
dc.subjectCalf thymus DNAen_US
dc.subjectSpectroscopyen_US
dc.subjectNanoparticlesen_US
dc.titleInvestigation on the interaction of dietary phenolic acids and their derivatives with biologically significant molecules A multi spectroscopic analysis.en_US
dc.typetexten_US
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